A 53 yrs old male patient with sob

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UNIT 1 ADMISSION : 


Unit 1 admission : 

Icu bed 3 

 A 53 year old male ,cycle repairer by occupation  came to the opd with chief complaints  shortness of breath since 45 mins 

C/O pedal edema in left leg upto ankle since 15 days 

C/O cough with blood tinged sputum since 15 days 


Pt was apparently asymptomatic 1 month back when he had 6 - 7 episodes of vomitings , associated with pain abdomen and loose stools (4- 5 episodes /day )for which he was admitted in government hospital and was given I .v fluids with loose stools persistent but decreased frequency since then  ,not associated with fever .

He then developed pedal edema associated with cough with sputum which is blood tinged scanty,not associated with chest pain , associated with intermittent SOB which decreased on treatment 

Pt continued to smoke 1 pack cigarrete /day ,after smoking he suddenly developed SOB at rest for 45 mins  associated with profuse sweating and was brought here 


H/O decreased urine output since 1 month 


History of chest pain  6 months back diagnosed as MI ,PTCA ( ? 2 DES ) not on regular follow up

 In the month of April, patient had sudden onset sob , profuse sweating, and retrosternal pain for which he was taken to a hospital near nalgonda where they thrombolysed him with streptokinase , after which they send him to Hyderabad where he underwent ptca , where a drug eluding stent to LCX was placed,

He was started on dual anti platelets and statin, after which he didn't have symptoms of sob or pedal edema till 15 days prior to admission,

He underwent ptca approximately one day after he was thrombolysed

Chronic smoker since 40 -45 days 

,1 pack cigarette /day 

Chronic alcoholic since 30 yrs,stopped 6 months back 

H/O right lower limb below knee amputation 3p yrs back (RTA)


Pt is conscious, coherent,cooperative 


No signs of pallor,icterus,cyanosis,clubbing, lymphadenopathy,edema 


Vitals : 

Temp - Afebrile 

Pr: 130 /min ,low volume 

Bp : not recordable 

Spo2 : 56 %

Grbs : 123 mg/dl 


CVS : S1,S2 heard 


RS : dyspnea present 

Breath sounds decreased in rt side 

Coarse crepitus in left ISA ,IMA ,IAA


P/A : 

distended abdomen 

,Shifting dullness present 

Bowel sounds heard




 Diagnosis:

A -cardiogenic shock secondary to HFrEF with TYPE 1 Respiratory failure secondary to moderate hemorrhagic pleural effusion secondary to ?consolidation ,?malignancy with K/C/O CAD S/P  PTCA  ( 2 drug eluting stents )2 LCX 6 months back, AKI(pre renal ) with ischemic  hepatitis

 Patient was intubated at 2am and extubated at 1 pm today

INVESTIGATIONS : 

Chest xray:


ECG AT THE TIME OF ADMISSION:


ECG AFTER SHIFTING TO ICU:



Hb -  13.9 

TLC - 17700 

RBC - 4.91 

PLT - 1.16 

 

CUE

ALB:+

EPITHELIAL CELLS:2-3 cells

PUS CELLS-  3-4 cells

urea - 70 mg/dl


Creat - 1.3 

Na - 127 

K - 5.1

Cl - 92 


Tb- 2.93 

Db - 0.95

AST - 83 

ALT - 44

ALP - 213

TP - 5.9 

albumin - 2.3 

A/G ration  - 0.65 


Rat - negative 

Serology - negative 

BT: 2 min

CT:4 min 30 sec

PT- 18sec

INR- 1.2

Ldh - 790.7 IU/L

PLEURAL FLUID









SUGAR - 40 mg/dl

Ldh - 1153


PLEURAL FLUID CYTOLOGY

color- slightly reddish, appearence- hazy

TLC- 15,200 cells/cu.mm

N- 20

L-80

SERUM LIPASE-39


PLEURAL FLUID CYTOLOGY

cyto smear shows acute inflammatory  exudates with neutrophils, occasional lymphocytes,  reactive mesoepithelial cells over pale proteinecious  background

Hb- 0.06 

Pcv-0.2

USG CHEST


USG ABDOMEN

 

ENDOTRACHEAL TUBE AFTER EXTUBATION


CHEST XRAY AFTER PLEURAL TAP
CHEST XRAY ON 8/9/21

2D ECHO



CTPA WAS DONE ON 9/9/21










On 8/9/21

HB- 11.6
TLC-18,700
PLT- 1.50
RBC-4.08

LFT: 

TB- 4.87
DB-2.82
AST- 68
ALT-41
ALP-183
TP-4.4
ALB-1.8

RFT

UREA-141
CREATININE-1.9
Ca2+: 8.2
Na+: 129
K+: 4.5
Cl- : 98

On 9/9/21

HB-11.2
TLC-17,700
RBC-3.98
PLT-1.46

RFT

UREA- 146
CREATININE-1.7
URICACID-7.7
Ca2+: 9.9
Na+:131
K+:3.7
Cl-: 96

On 10/9/21

HB-10.6
TLC-18,500
RBC-3.79
PLT-1.50

PT-16sec
INR-1.11


RFT

UREA- 152
CREATININE-2
URICACID-7.2
Ca2+: 8.3
Na+:130
K+:4.9
Cl-: 95

On 11/9/21

HB-10.9
TLC-20,500
RBC-3.89
PLT-1.54


LFT: 

TB- 5.67
DB-2.89
AST- 48
ALT-30
ALP-185
TP-5.1
ALB-2

RFT

UREA-146
CREATININE-2
Ca2+: 9.1
Na+: 131
K+: 4.3
Cl- : 96

PT: 18 sec
INR- 1.3 

Soap notes :

Day 2  of admission : 

S - SOB with sats 56% at the time of admission 
Intubated at 2 am yesterday and extubated at 1 pm 
Pleural tap done 

Patient subjectively feeling better with no fresh complaints 

O -Temp : Afebrile 
     Bp : 90/60   
     Pr : 110 bpm
     Spo2: 92 
     CVS : S1,S2 heard 
     RS : BAE  on left side is decreased in isa,ma ,absent air entry on right side isa, iaa, ma
   

A -cardiogenic shock secondary to HFrEF with TYPE 1 Respiratory failure secondary to moderate hemorrhagic pleural effusion secondary to ?consolidation ,?malignancy with K/C/O CAD S/P  PTCA  ( 2 drug eluting stents )2 LCX 6 months back, AKI(pre renal ) with ischemic  hepatitis

P-propped upto 30degrees
-Ryles tube feed-  50 ml milk 2 nd hrly
                                100 ml water 4 th hrly
- ryles tube suctioning before intake of food 2 nd hrly
-INJ PIPTAZ 4.5 mg/IV/ STAT
 INJ PIPTAZ 4.5 mg /IV/TID
-INJ PANTOP 40mg /IV/ OD
- INJ NORAD- DS 10 ml/ hr 
- INJ DOBUTAMINE 2 AMP IN 50 ml  NS at 6 ml / hr
- INJ LASIX 5 AMP IN 30 ml ns at 4 ml / hr
- INJ THIAMINE 100 mg IV/ TID in 100 ml ns
- INJ LEVOFLOXACIN 500 mg IV / OD
- TAB ECOSPRIN - AV 75/20 mg rt/ hs



Soap notes :

Day 3  of admission : 


S-Patient subjectively feeling better with complaints of cough

O -Temp : 98.7F
     Bp : 90/70mmhg on 12 ml/hr  dobutamine, 25ml/hr noradrenaline
     Pr : 140bpm ,irregular, low volume
     Rr:35 cpm
     Spo2: 98% on 8 litres oxygen
     CVS : S1,S2 heard 
     RS : BAE +,decreased       breath sounds on right side
   

A -cardiogenic shock secondary to HFrEF with TYPE 1 Respiratory failure secondary to right massive pleural effusion secondary to consolidation with K/C/O CAD S/P  PTCA  ( 2 DES )6 months back ? Nosocomial
Pneumonia? pulmonary embolism

P-propped upto 30degrees
-INJ PIPTAZ 4.5 mg/IV/ STAT
 INJ PIPTAZ 4.5 mg /IV/TID
-INJ PANTOP 40mg /IV/ OD
- INJ NORAD- DS 20 ml/ hr 
- INJ DOBUTAMINE 2 AMP IN 50 ml  NS at 12 ml / hr
- INJ LASIX 5 AMP IN 30 ml ns at 4 ml / hr
- INJ THIAMINE 100 mg IV/ TID in 100 ml ns
-TAB ECOSPRIN - AV 75/20 mg rt/ hs
- NEB WITH IPRAVENT(6 th hrly) BUDECORT (12 th hrly)
-INJ PCM 650mg PO/ SOS

Soap notes :

Day 4  of admission : 

ICU bed -3
Pt is C/C/C
Pedal edema persistent
S- C/O SOB on lying flat 

O -Temp : 98.7
     Bp : 90/70mmhg on 12ml/hr  dobutamine, 22ml/hr noradrenaline
     Pr : 111 bpm ,irregular, low volume
     Rr:28 cpm
     Spo2: 88% on RA in sitting, 96% on 12 lit oxygen
     CVS : S1,S2 heard 
     RS : BAE + ,decreased       breath sounds in, Rt infraaxiallary area, infrascapular areas
   

A -cardiogenic shock secondary to HFrEFwith EF 30% with TYPE 1 RESPIRATORY FAILURE (WITH NIV) secondary to consolidation with HAEMORRAHAGIC RT PLEURAL EFFUSION secondary to acute  pulmonary embolism  with contarst induced nephropathy with ischemic hepatitis with thrombus in rt atria and left atrial appendage ,ventricular apex,descending aorta



P- soft oral diet, oral fluids upto 1 lit
- O2 inhalation@4-6 lit/ min
 -INJ PIPTAZ 4.5 mg /IV/TID
-INJ PANTOP 40mg /IV/ OD
- INJ NORAD- DS 22ml/ hr 
- INJ DOBUTAMINE 2 AMP IN 50 ml  NS at 10ml / hr
-INJ HEPARIN INFUSION 800 IU/hr 1.8 ml/ hr for 24 hrs
- INJ THIAMINE 100 mg IV/ TID in 100 ml ns
-TAB ECOSPRIN - AV 75/20 mg rt/ hs
- NEB WITH IPRAVENT(6 th hrly) BUDECORT (12 th hrly)
-INJ PCM 650mg PO/ SOS

Soap notes :

Day 5  of admission : 

ICU bed -3
Pt is C/C/C
Pedal edema persistent
S- C/O SOB on lying flat 

O -Temp : 98.7
     Bp : 90/70mmhg on 12ml/hr  dobutamine, 22ml/hr noradrenaline
     Pr : 111 bpm ,irregular, low volume
     Rr:28 cpm
     Spo2: 88% on RA in sitting, 96% on 12 lit oxygen
     CVS : S1,S2 heard 
     RS : BAE + ,decreased       breath sounds in, Rt infraaxiallary area, infrascapular areas
   

A -cardiogenic shock secondary to HFrEFwith EF 30% with TYPE 1 RESPIRATORY FAILURE (WITH NIV) secondary to consolidation with HAEMORRAHAGIC RT PLEURAL EFFUSION secondary to acute  pulmonary embolism  with contarst induced nephropathy with ischemic hepatitis with thrombus in rt atria and left atrial appendage ,ventricular apex,descending aorta


P- soft oral diet, oral fluids upto 1 lit
- O2 inhalation@4-6 lit/ min
 INJ PIPTAZ 4.5 mg /IV/BD
-INJ PANTOP 40mg /IV/ OD
- INJ NORAD- DS 22ml/ hr 
- INJ DOBUTAMINE 250 MCG IN 50 ml  NS at 12ml / hr
-TAB ECOSPRIN - AV 75/20 mg rt/ hs
-INJ.ACETYLCYSTEINE  600 MG /IV/BD

 TREATMENT  GIVEN
Day1
- propped upto 30degrees
-Ryles tube feed-  50 ml milk 2 nd hrly
                                100 ml water 4 th hrly
- ryles tube suctioning before intake of food 2 nd hrly
-INJ PIPTAZ 4.5 mg/IV/ STAT
 INJ PIPTAZ 4.5 mg /IV/TID
-INJ PANTOP 40mg /IV/ OD
- INJ NORAD- DS 10 ml/ hr 
- INJ DOBUTAMINE 2 AMP IN 50 ml  NS at 6 ml / hr
- INJ LASIX 5 AMP IN 30 ml ns at 4 ml / hr
- INJ THIAMINE 100 mg IV/ TID in 100 ml ns
- INJ LEVOFLOXACIN 500 mg IV / OD
- TAB ECOSPRIN - AV 75/20 mg rt/ hs


Day 2
propped upto 30degrees
-Ryles tube feed-  50 ml milk 2 nd hrly
                                100 ml water 4 th hrly
- ryles tube suctioning before intake of food 2 nd hrly
-INJ PIPTAZ 4.5 mg/IV/ STAT
 INJ PIPTAZ 4.5 mg /IV/TID
-INJ PANTOP 40mg /IV/ OD
- INJ NORAD- DS 10 ml/ hr 
- INJ DOBUTAMINE 2 AMP IN 50 ml  NS at 6 ml / hr
- INJ LASIX 5 AMP IN 30 ml ns at 4 ml / hr
- INJ THIAMINE 100 mg IV/ TID in 100 ml ns
- INJ LEVOFLOXACIN 500 mg IV / OD
- TAB ECOSPRIN - AV 75/20 mg rt/ hs

Day 3
-propped upto 30degrees
-INJ PIPTAZ 4.5 mg/IV/ STAT
 INJ PIPTAZ 4.5 mg /IV/TID
-INJ PANTOP 40mg /IV/ OD
- INJ NORAD- DS 20 ml/ hr 
- INJ DOBUTAMINE 2 AMP IN 50 ml  NS at 12 ml / hr
- INJ LASIX 5 AMP IN 30 ml ns at 4 ml / hr
- INJ THIAMINE 100 mg IV/ TID in 100 ml ns
-TAB ECOSPRIN - AV 75/20 mg rt/ hs
- NEB WITH IPRAVENT(6 th hrly) BUDECORT (12 th hrly)
-INJ PCM 650mg PO/ SOS


Day-4
- soft oral diet, oral fluids upto 1 lit
- O2 inhalation@4-6 lit/ min
 -INJ PIPTAZ 4.5 mg /IV/TID
-INJ PANTOP 40mg /IV/ OD
- INJ NORAD- DS 22ml/ hr 
- INJ DOBUTAMINE 2 AMP IN 50 ml  NS at 10ml / hr
-INJ HEPARIN INFUSION 800 IU/hr 1.8 ml/ hr for 24 hrs
- INJ THIAMINE 100 mg IV/ TID in 100 ml ns
-TAB ECOSPRIN - AV 75/20 mg rt/ hs
- NEB WITH IPRAVENT(6 th hrly) BUDECORT (12 th hrly)
-INJ PCM 650mg PO/ SOS

Day-5
soft oral diet, oral fluids upto 1 lit
- O2 inhalation@4-6 lit/ min
 INJ PIPTAZ 4.5 mg /IV/BD
-INJ PANTOP 40mg /IV/ OD
- INJ NORAD- DS 22ml/ hr 
- INJ DOBUTAMINE 250 MCG IN 50 ml  NS at 12ml / hr
-TAB ECOSPRIN - AV 75/20 mg rt/ hs
-INJ.ACETYLCYSTEINE  600 MG /IV/BD





DEATH SUMMARY:

A 53 yr old cycle repaired by occupation presented to casuality  With since 45 mins  shortness of breath associated with cough with blood tinged sputum since 15 days , spo2 on presentation is 56%on room air , 64%on 15lit of o2, consentfor intubation was taken and was intubated , pulse, bp not recordable, carotid pulsations felt(112/min)  and was started on vasopressors( noradrenaline, dobutamine) and was diagnosed to be in cardiogenic shock  secondary to HFrEF  with EF-30% with thrombus in right atria, LL atrial appendage, vent apex DEST aorta, CAD -S/P PTCA, DES TO LCX
Inj  heparin infusion was started @1.8 ml/hr
Thoracocentesis  was done in view hemorrhagic pleural effusion 
Around 1:30 am on 12/9/21-bp , pulse not recordable, cpr was started according to ACLS guidelines. Despite the above resuscitation, treatment patient could not be revived and wqs declered dead on 12/9 /21@1:59 am

 Immediate cause of death- sudden cardiac arrest secondary to cardiogenic shock

Antecedant cause of death : type 1 respiratory failure( with NIV) secondary to right  consolidation with hemmorhagic right pleural effusion secondary to acute pulmonary embolism with ischemic hepatitis with thrombus in right atria, LL atrial appendage , vent apex , DEST  aorta
 CAD- S/P PTCA, DES TO LCX









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