A 74 yr old female with fever

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Unit 1 admission 

Amc


A 74 year old female came with complaints of fever since 4 days,generalised weakness since 4days

SOB on exertion since 3 days,which progressed to SOB on rest today morning 

H/o two episodes of vomiting 1 day ago 

Hopi:

Pt was apparently asymptomatic 4 days ago,c/o fever,highgrade,intermittent,not associated with chills and rigors 

Associated with generalized weakness, two episodes vomitings,subsided on its own

SOB on exertion then progressed to SOB on rest since today morning 

H/0 ?pericardial effusion 1year ago,diagnosed,on medication for 6 months later subsided

No h/o orthopnea,pnd

No pain  abdomen,loose stools

 

Past history:

K/c/o Dm since 3 years

K/c/o hypothyroidism since 10 years on regular medication

Personal history:

Diet:mixed

Appetite:normal

Bowel,Bladder:regular

No addictions 


General examination 

Pt is c/c/c

Pallor+,no icterus,cyanosis, clubbing, lymphadenopathy,edema

Vitals

Pr-86bpm

Bp-100/70mmhg

Rr-24cpm

Spo2-95%@RA

Grbs-146mg/dl


Systemic examination 

Cvs-s1,s2+

Rs-crepts+

Nvbs

P/a:

Soft,nontender

No palpable mass

Cns-intact


Provisional diagnosis:

 LEPTOSPIRA WITH RENAL AKI WITH UREMIC ENCPHALOPATHY WITH HEPATIC ENCEPHALOPATHY GRADE 1 ( RESOLVED)

WITH DM -2 , HTN  , HYPOTHYROIDISM

Investigations:

Plt at time of admission- 20,000/ cu.mm

Aptt-41.0

Inr-1.21

Dengue Ns1-negative

DengueIgG-negative

Dengue IgM-negative

Serology- negative


On 14/9/21  (morning  sample)

Hb-7.9gm

Tlc-26,500 cells/ cu.mm

Rbc- 2.89 millions/ cu.mm

Plt-32000/cu.mm



Lft

Tb-8.49

Db- 6.06

Ast-87

Alt-41

Alp-314

Alb-2.36

Tp-5.9

Rft

Urea-187

Creatinine-4

Na+ 120

K+ 5.3

Cl- 96



On 14/9/21 

Hb- 7.9 gm

Tlc-32,500 cells/ cu.mm

Rbc-2.89 millions/ cu.mm

Plt- 35,000 lakhs/cu.mm


Crusting of lips



Chest x ray






Repeat X ray  on 17/09/21








Ecg



2D echo





ON 15 /9/21

Hb-7.4
Tlc- 30,200
Plt- 20,000
Pcv- 20.7

Urea- 237
Creatinine- 4.8

Serum electrolytes
Na+ 128
K+ 5.1
Cl- 94

Urinary electrolytes
Na+ 167
K+ 32
Cl- 196

APTT- 29 sec
PT- 14 sec
INR- 1

On 17/09/21

HEMOGRAM
Hb- 6.1
Tlc- 23,600
Plt- 30,000
Pcv-16.5
Rbc- 2.20

Thyroid profile
T3 - 0.60
T4- 4.64
TSH- 3.08

Peripheral smear




On 18/09/21
Hemogram

Hb- 6.1
Tlc-18,300
Pcv- 16.7
Rbc-2.25
Plt- 40,000

Rft:
Serum creatinine- 2.5
Blood urea- 167

Serum electrolytes
Na+ 131
K+4.1
Cl- 96

Lft:
Tb- 2.71
Db- 0.60
Ast- 50
Alt - 46
Alp- 262
Tp- 4.9.
Alb- 2.3
A/G- 0.89

On 21/9/21

Hb- 5.5
Tlc- 11,800
Rbc- 2.04
Plt- 1.1



TREATMENT GIVEN:

day 2

1)IVF (RL, NS)
2) INJ PAN 40 mg IV/OD
3) INJ ZOFER 4mgIV/ BD
4)INJ HAI S/C ACC TO GRBS( 8 am-- 1pm---8pm)
5) TAB PCM  650 mg PO/TID 
6) O2  inhalatiin @ 4 lit/min
7) NEB BUDICORT( 12 th hrly)
              DUBOLIN( 8th hrly)
8) INJ  DOXY 100 mg PO/BD 
9) INJ CEFTRIAXONE 1gm /IV/ BD
10) INJ FALCIGO 120mg IV/ STAT
11) monitor vitals

Day 3
1.IVF NS and RL @100ml/hr
2.INJ.PANTOP 40mg/IV/OD
3.INJ.MONOCEF 1g /IV/BD
4.INJ.DOXYCYCLINE 100mg/PO/BD
4.INJ.FLACIGO 120mg IV/24hrs
5.INJ.HAI s/c TID before meals.
6.SYP.LACTULOSE 30ml PO/BD.

Day 4

1.IVF NS and RL @100ml/hr
2.INJ.PANTOP 40mg/IV/OD
3.INJ.MONOCEF 1g /IV/BD
4.INJ.DOXYCYCLINE 100mg/PO/BD
4.INJ.FLACIGO 120mg IV/48hrs
5.INJ.HAI s/c TID before meals.
6.SYP.LACTULOSE 30ml PO/BD.
7. PROTEIN POWDER


Day 5
1.IVF NS and RL @100ml/hr
2.INJ.PANTOP 40mg/IV/OD
3.INJ.MONOCEF 1g /IV/BD
4.INJ.DOXYCYCLINE 100mg/PO/BD
4.INJ.FLACIGO 120mg IV/48hrs
5.INJ.HAI s/c TID before meals.
6.SYP.LACTULOSE 30ml PO/BD.
7. PROTEIN POWDER
8. T.THYRONORM 100 micrograms PO/ OD
9.NEB WITH BUDICIRT, DUBOLIN
10. SYP GRILLINTUS 10 ml PO/ BD


Day 6 
1.IVF NS and RL @100ml/hr
2.INJ.PANTOP 40mg/IV/OD
3.INJ.MONOCEF 1g /IV/BD
4.INJ.DOXYCYCLINE 100mg/PO/BD
5.INJ.HAI s/c TID before meals.
6.SYP.LACTULOSE 30ml PO/BD.
7. PROTEIN POWDER
8. T.THYRONORM 100 micrograms PO/ OD
9.NEB WITH BUDICIRT, DUBOLIN
10. SYP GRILLINTUS 10 ml PO/ BD

Day 7
1.IVF NS and RL @100ml/hr
2.INJ.PANTOP 40mg/IV/OD
3.INJ.MONOCEF 1g /IV/BD
4.INJ.DOXYCYCLINE 100mg/PO/BD
5.INJ.HAI s/c TID before meals.
6.SYP.LACTULOSE 30ml PO/BD.
7. PROTEIN POWDER
8. T.THYRONORM 100 micrograms PO/ OD
9.NEB WITH BUDICIRT, DUBOLIN
10. SYP GRILLINTUS 10 ml PO/ BD

Day 8

1.IVF NS and RL @100ml/hr
2.INJ.PANTOP 40mg/IV/OD
3.INJ.MONOCEF 1g /IV/BD
4.INJ.DOXYCYCLINE 100mg/PO/BD
4.INJ.HAI s/c TID before meals.
5.SYP.LACTULOSE 30ml PO/BD.
6.PROTEIN POWDER 
7.T.THYRONORM 100 micrograms PO/ OD
10.NEB WITH BUDICIRT, DUBOLIN
11. SYP GRILLINTUS 10 ml PO/ BD
12. Inj.OPTINEURON 1 AMP IN 100 ML NS IV/OD
13.TAB.ULTRACET 1/2 TAB PO/ QID


Day 9
1.INJ.HAI s/c TID before meals.
2.SYP.LACTULOSE 30ml PO/BD.
3.PROTEIN POWDER 
4.T.THYRONORM 100 micrograms PO/ OD
5.NEB WITH BUDICORT, DUBOLIN
6. SYP GRILLINTUS 10 ml PO/ BD
7.TAB.ULTRACET 1/2 TAB PO/ QID
8. CHEST PHYSIOTHERAPY












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